{"id":55957,"date":"2026-04-21T16:04:38","date_gmt":"2026-04-21T12:04:38","guid":{"rendered":"https:\/\/mkhare.ge\/?p=55957"},"modified":"2026-04-21T16:04:38","modified_gmt":"2026-04-21T12:04:38","slug":"%e1%83%92%e1%83%98%e1%83%9d%e1%83%a0%e1%83%92%e1%83%98-%e1%83%a4%e1%83%ae%e1%83%90%e1%83%99%e1%83%90%e1%83%ab%e1%83%94-%e1%83%a7%e1%83%95%e1%83%94%e1%83%9a%e1%83%90%e1%83%96%e1%83%94-%e1%83%93","status":"publish","type":"post","link":"https:\/\/mkhare.ge\/?p=55957","title":{"rendered":"\u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4: \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e8\u10d4\u10ea\u10d3\u10dd\u10db\u10d0\u10d0 \u10d8\u10e1, \u10e0\u10dd\u10db \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10e1 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10e4\u10d0\u10e1\u10e1 \u10d3\u10d0 \u10d8\u10db\u10d4\u10d3\u10e1, \u10db\u10d0\u10d2\u10e0\u10d0\u10db \u10d0\u10e0 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10e1. \u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0\u10e8\u10d8 \u10e0\u10d8\u10e1\u10d9\u10d8\u10e1 \u10d3\u10d0\u10db\u10d0\u10da\u10d5\u10d0 \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10d4\u10d0 &#8211; \u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd, \u10db\u10d0\u10e0\u10e2\u10d8\u10d5\u10d8 \u10d0\u10dc \u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0"},"content":{"rendered":"<p>\u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e8\u10d4\u10ea\u10d3\u10dd\u10db\u10d0 \u10d3\u10e6\u10d4\u10e1 \u10d0\u10e0\u10d8\u10e1 \u10d8\u10e1, \u10e0\u10dd\u10db \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10e1 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10e4\u10d0\u10e1\u10e1 \u10d3\u10d0 \u201e\u10d8\u10db\u10d4\u10d3\u10e1\u201c, \u10db\u10d0\u10d2\u10e0\u10d0\u10db \u10d0\u10e0 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10e1. \u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0\u10e8\u10d8 \u10e0\u10d8\u10e1\u10d9\u10d8\u10e1 \u10d3\u10d0\u10db\u10d0\u10da\u10d5\u10d0 \u2014 \u10d0\u10e0\u10d8\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10d4. \u10db\u10d7\u10d0\u10d5\u10d0\u10e0\u10d8 \u10e4\u10d0\u10e5\u10e2\u10d8 (\u10e0\u10d0\u10ea \u10d0\u10e3\u10ea\u10d8\u10da\u10d4\u10d1\u10da\u10d0\u10d3 \u10e3\u10dc\u10d3\u10d0 \u10d8\u10ea\u10dd\u10d3\u10d4\u10e1 \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10db), \u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd, \u10db\u10d0\u10e0\u10e2\u10d8\u10d5\u10d8 \u10d0\u10dc \u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0, &#8211; \u10ec\u10d4\u10e0\u10e1 \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10d4\u10e5\u10e1\u10de\u10d4\u10e0\u10e2\u10d8 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4 7 \u10d0\u10de\u10e0\u10d8\u10da\u10e1 \u10e1\u10dd\u10ea\u10d8\u10d0\u10da\u10e3\u10e0 \u10e5\u10e1\u10d4\u10da\u10e8\u10d8 \u10d2\u10d0\u10db\u10dd\u10e5\u10d5\u10d4\u10e7\u10dc\u10d4\u10d1\u10d8\u10da \u10de\u10dd\u10e1\u10e2\u10e8\u10d8.<\/p>\n<p>\u201e\u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10d9\u10e3\u10dc\u10d7\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d3\u10d8\u10e1\u10e2\u10e0\u10dd\u10e4\u10d8\u10d0 \u2014 \u10e1\u10e0\u10e3\u10da\u10d8 \u10e1\u10d8\u10db\u10d0\u10e0\u10d7\u10da\u10d4: \u10d4\u10e4\u10d4\u10e5\u10e2\u10e3\u10e0\u10dd\u10d1\u10d0, \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10d8 \u10d3\u10d0 \u10e0\u10d4\u10d2\u10e3\u10da\u10d0\u10ea\u10d8\u10d0<\/p>\n<p>\u201e\u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e8\u10d4\u10ea\u10d3\u10dd\u10db\u10d0 \u10d3\u10e6\u10d4\u10e1 \u10d0\u10e0\u10d8\u10e1 \u10d8\u10e1, \u10e0\u10dd\u10db \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10e1 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10e4\u10d0\u10e1\u10e1 \u10d3\u10d0 \u201e\u10d8\u10db\u10d4\u10d3\u10e1\u201c, \u10db\u10d0\u10d2\u10e0\u10d0\u10db \u10d0\u10e0 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10e1.<\/p>\n<p>\u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0\u10e8\u10d8 \u10e0\u10d8\u10e1\u10d9\u10d8\u10e1 \u10d3\u10d0\u10db\u10d0\u10da\u10d5\u10d0 \u2014 \u10d0\u10e0\u10d8\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10d4.\u201c<\/p>\n<p>\u2757\u10db\u10d7\u10d0\u10d5\u10d0\u10e0\u10d8 \u10e4\u10d0\u10e5\u10e2\u10d8 (\u10e0\u10d0\u10ea \u10d0\u10e3\u10ea\u10d8\u10da\u10d4\u10d1\u10da\u10d0\u10d3 \u10e3\u10dc\u10d3\u10d0 \u10d8\u10ea\u10dd\u10d3\u10d4\u10e1 \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10db)<\/p>\n<p>\u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 = \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd, \u10db\u10d0\u10e0\u10e2\u10d8\u10d5\u10d8 \u10d0\u10dc \u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0<\/p>\n<p>\u10e7\u10d5\u10d4\u10da\u10d0 \u10ec\u10d0\u10db\u10d0\u10da\u10e1 \u10d0\u10e5\u10d5\u10e1: \u10e8\u10d4\u10d6\u10e6\u10e3\u10d3\u10e3\u10da\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d8, \u10e1\u10d4\u10e0\u10d8\u10dd\u10d6\u10e3\u10da\u10d8 \u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8, \u10d2\u10d0\u10dc\u10e1\u10ee\u10d5\u10d0\u10d5\u10d4\u10d1\u10e3\u10da\u10d8 \u10e0\u10d4\u10d2\u10e3\u10da\u10d0\u10ea\u10d8\u10e3\u10e0\u10d8 \u10e1\u10e2\u10d0\u10e2\u10e3\u10e1\u10d8 (FDA vs EU)<\/p>\n<p>1. Elevidys (\u10d2\u10d4\u10dc\u10dd\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0)<\/p>\n<p>FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 (\u10e8\u10d4\u10d6\u10e6\u10e3\u10d3\u10e3\u10da\u10d0\u10d3)<\/p>\n<p>EU (EMA): \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8<\/p>\n<p>\u10e4\u10d0\u10e1\u10d8: ~3.2 \u10db\u10d8\u10da\u10d8\u10dd\u10dc\u10d8 \u10d3\u10dd\u10da\u10d0\u10e0\u10d8 (\u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8)<\/p>\n<p>\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8 (\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8): \u10db\u10ec\u10d5\u10d0\u10d5\u10d4 \u10e6\u10d5\u10d8\u10eb\u10da\u10d8\u10e1 \u10d3\u10d0\u10d6\u10d8\u10d0\u10dc\u10d4\u10d1\u10d0, \u10f0\u10dd\u10e1\u10de\u10d8\u10e2\u10d0\u10da\u10d8\u10d6\u10d0\u10ea\u10d8\u10d0, \u10d3\u10d0\u10e4\u10d8\u10e5\u10e1\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 \u10e1\u10d8\u10d9\u10d5\u10d3\u10d8\u10da\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10d8, \u10db\u10d8\u10dd\u10d9\u10d0\u10e0\u10d3\u10d8\u10e2\u10d8 (\u10d2\u10e3\u10da\u10d8\u10e1 \u10d0\u10dc\u10d7\u10d4\u10d1\u10d0), \u10db\u10d8\u10dd\u10d6\u10d8\u10e2\u10d8 (\u10d9\u10e3\u10dc\u10d7\u10d8\u10e1 \u10d0\u10dc\u10d7\u10d4\u10d1\u10d0), \u10d8\u10db\u10e3\u10dc\u10e3\u10e0\u10d8 \u10e0\u10d4\u10d0\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8.<\/p>\n<p>FDA \u10e3\u10d9\u10d5\u10d4 \u10d8\u10eb\u10d8\u10d4\u10d1\u10e1 \u10d0\u10db \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10e1 \u10d3\u10d0 \u10d3\u10d0\u10d0\u10db\u10d0\u10e2\u10d0 \u10db\u10d9\u10d0\u10ea\u10e0\u10d8 \u10d2\u10d0\u10e4\u10e0\u10d7\u10ee\u10d8\u10da\u10d4\u10d1\u10d4\u10d1\u10d8<\/p>\n<p>\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8: \u10d4\u10e1 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10e0\u10e3\u10da\u10d0\u10d3 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd, \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u201e\u10e1\u10d0\u10e1\u10ec\u10d0\u10e3\u10da\u10d8 \u10d2\u10d0\u10db\u10dd\u10e1\u10d0\u10d5\u10d0\u10da\u10d8\u201c.<\/p>\n<p>2. Duvyzat (givinostat)<\/p>\n<p>FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 (2024)<\/p>\n<p>EU: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n<p>\u10e4\u10d0\u10e1\u10d8: ~700,000$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n<p>\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10d3\u10d8\u10d0\u10e0\u10d4\u10d0, \u10d2\u10e3\u10da\u10d8\u10e1\u10e0\u10d4\u10d5\u10d0 \/ \u10e6\u10d4\u10d1\u10d8\u10dc\u10d4\u10d1\u10d0, \u10d7\u10e0\u10dd\u10db\u10d1\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10d0 (\u10e1\u10d8\u10e1\u10ee\u10da\u10d3\u10d4\u10dc\u10d8\u10e1 \u10e0\u10d8\u10e1\u10d9\u10d8), \u10ea\u10ee\u10d8\u10db\u10d4\u10d1\u10d8\u10e1 \u10db\u10d0\u10e2\u10d4\u10d1\u10d0 \u10e1\u10d8\u10e1\u10ee\u10da\u10e8\u10d8, \u10e1\u10d8\u10ea\u10ee\u10d4.<\/p>\n<p>3. Agamree (vamorolone)<\/p>\n<p>FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 (2023)<\/p>\n<p>EU: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n<p>\u10e4\u10d0\u10e1\u10d8: ~50,000\u2013100,000$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n<p>\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10f0\u10dd\u10e0\u10db\u10dd\u10dc\u10d0\u10da\u10e3\u10e0\u10d8 \u10d3\u10d0\u10e0\u10e6\u10d5\u10d4\u10d5\u10d4\u10d1\u10d8 (Cushing-like), \u10ec\u10dd\u10dc\u10d8\u10e1 \u10db\u10d0\u10e2\u10d4\u10d1\u10d0, \u10e4\u10e1\u10d8\u10e5\u10d8\u10d9\u10e3\u10e0\u10d8 \u10ea\u10d5\u10da\u10d8\u10da\u10d4\u10d1\u10d4\u10d1\u10d8 (\u10d0\u10d2\u10e0\u10d4\u10e1\u10d8\u10d0, \u10e8\u10e4\u10dd\u10d7\u10d5\u10d0), \u10d8\u10db\u10e3\u10dc\u10d8\u10e2\u10d4\u10e2\u10d8\u10e1 \u10d3\u10d0\u10e5\u10d5\u10d4\u10d8\u10d7\u10d4\u10d1\u10d0, \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8\u10e1 \u10e0\u10d8\u10e1\u10d9\u10d8, \u10d0\u10d3\u10e0\u10d4\u10dc\u10d0\u10da\u10e3\u10e0\u10d8 \u10e3\u10d9\u10db\u10d0\u10e0\u10d8\u10e1\u10dd\u10d1\u10d0.<\/p>\n<p>4. Exon-skipping \u10de\u10e0\u10d4\u10de\u10d0\u10e0\u10d0\u10e2\u10d4\u10d1\u10d8 (Exondys, Vyondys \u10d3\u10d0 \u10e1\u10ee\u10d5.)<\/p>\n<p>FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 (Accelerated approval)<\/p>\n<p>EU: \u10eb\u10d8\u10e0\u10d8\u10d7\u10d0\u10d3\u10d0\u10d3 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8<\/p>\n<p>\u10e4\u10d0\u10e1\u10d8: ~300,000 \u2013 1,000,000+$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n<p>\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8, \u10ee\u10d5\u10d4\u10da\u10d0, \u10e1\u10d8\u10ea\u10ee\u10d4, \u10d7\u10d8\u10e0\u10d9\u10db\u10da\u10d8\u10e1 \u10d2\u10d0\u10e0\u10d7\u10e3\u10da\u10d4\u10d1\u10d4\u10d1\u10d8, \u10d8\u10dc\u10d4\u10e5\u10ea\u10d8\u10d8\u10e1 \u10d0\u10d3\u10d2\u10d8\u10da\u10d6\u10d4 \u10e0\u10d4\u10d0\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8, \u10e6\u10d4\u10d1\u10d8\u10dc\u10d4\u10d1\u10d0, \u10d2\u10d0\u10db\u10dd\u10dc\u10d0\u10e7\u10d0\u10e0\u10d8, \u10e1\u10d0\u10ee\u10e1\u10e0\u10d4\u10d1\u10d8\u10e1 \u10e2\u10d9\u10d8\u10d5\u10d8\u10da\u10d8.<\/p>\n<p>\ud83d\udce2\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8: \u10db\u10e3\u10e8\u10d0\u10dd\u10d1\u10e1 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 5\u201315% \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d6\u10d4 (\u10d2\u10d4\u10dc\u10d4\u10e2\u10d8\u10d9\u10d8\u10e1 \u10db\u10d8\u10ee\u10d4\u10d3\u10d5\u10d8\u10d7)<\/p>\n<p>5. \u10e1\u10e2\u10d0\u10dc\u10d3\u10d0\u10e0\u10e2\u10e3\u10da\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 (Deflazacort)<\/p>\n<p>FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n<p>EU: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n<p>\u10e4\u10d0\u10e1\u10d8: ~35,000\u201360,000$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n<p>\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10d6\u10e0\u10d3\u10d8\u10e1 \u10e8\u10d4\u10e4\u10d4\u10e0\u10ee\u10d4\u10d1\u10d0, \u10dd\u10e1\u10e2\u10d4\u10dd\u10de\u10dd\u10e0\u10dd\u10d6\u10d8, \u10d3\u10d8\u10d0\u10d1\u10d4\u10e2\u10d8\u10e1 \u10e0\u10d8\u10e1\u10d9\u10d8, \u10ec\u10dd\u10dc\u10d8\u10e1 \u10db\u10d0\u10e2\u10d4\u10d1\u10d0, \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8<\/p>\n<p>\ud83d\udd2c\u10db\u10dd\u10db\u10d0\u10d5\u10d0\u10da\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d4\u10d1\u10d8 (\u10ef\u10d4\u10e0 \u10d9\u10d5\u10da\u10d4\u10d5\u10d8\u10e1 \u10d4\u10e2\u10d0\u10de\u10d6\u10d4)<\/p>\n<p>CRISPR \u10d2\u10d4\u10dc\u10e3\u10e0\u10d8 \u10e0\u10d4\u10d3\u10d0\u10e5\u10e2\u10d8\u10e0\u10d4\u10d1\u10d0<\/p>\n<p>\u10d0\u10ee\u10d0\u10da\u10d8 \u10d2\u10d4\u10dc\u10dd\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d4\u10d1\u10d8 (\u10e3\u10e4\u10e0\u10dd \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd \u10d5\u10d0\u10e0\u10d8\u10d0\u10dc\u10e2\u10d4\u10d1\u10d8)<\/p>\n<p>\u10d9\u10dd\u10db\u10d1\u10d8\u10dc\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0<\/p>\n<p>\u10db\u10d0\u10d2\u10e0\u10d0\u10db: \u10ef\u10d4\u10e0 \u10d0\u10e0\u10ea\u10d4\u10e0\u10d7\u10d8 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10e0\u10e3\u10da\u10d0\u10d3 \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8.<\/p>\n<p>\u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d3\u10d0\u10e1\u10d9\u10d5\u10dc\u10d0<\/p>\n<p>\u10d3\u10e6\u10d4\u10e1 \u10d0\u10e0\u10ea\u10d4\u10e0\u10d7\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0:<\/p>\n<p>\u274c\u10d0\u10e0 \u10d9\u10e3\u10e0\u10dc\u10d0\u10d5\u10e1 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d0\u10e1<\/p>\n<p>\u274c\u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10e0\u10e3\u10da\u10d0\u10d3 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd<\/p>\n<p>\u274c\u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e3\u10dc\u10d8\u10d5\u10d4\u10e0\u10e1\u10d0\u10da\u10e3\u10e0\u10d8<\/p>\n<p>\u10e0\u10d4\u10d0\u10da\u10e3\u10e0\u10d8 \u10d0\u10e0\u10e9\u10d4\u10d5\u10d0\u10dc\u10d8 \u10e5\u10d5\u10d4\u10e7\u10dc\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 &#8211;<\/p>\n<p>100 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d8 =<\/p>\n<p>\u10d2\u10d4\u10dc\u10dd\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 \u2192 ~300 \u10db\u10d8\u10da\u10d8\u10dd\u10dc\u10d8 $<\/p>\n<p>\u10d7\u10d0\u10dc\u10d0\u10db\u10d4\u10d3\u10e0\u10dd\u10d5\u10d4 \u10ec\u10d0\u10db\u10da\u10d4\u10d1\u10d8 \u2192 5\u201370 \u10db\u10d8\u10da\u10d8\u10dd\u10dc\u10d8 $\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n<p>\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10d9\u10d0\u10e4\u10d8\u10dd \u10d3\u10d0\u10e1\u10d9\u10d5\u10dc\u10d0 &#8211; \u10db\u10e8\u10dd\u10d1\u10da\u10d4\u10d1\u10d8\u10e1 \u10db\u10dd\u10d7\u10ee\u10dd\u10d5\u10dc\u10d0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10d0\u10db\u10d0\u10e0\u10d7\u10da\u10d8\u10d0\u10dc\u10d8. \u10db\u10d0\u10d2\u10e0\u10d0\u10db:<\/p>\n<p>\ud83d\udc49\u10e1\u10e0\u10e3\u10da\u10d8 \u10e1\u10d8\u10db\u10d0\u10e0\u10d7\u10da\u10d8\u10e1 \u10d2\u10d0\u10e0\u10d4\u10e8\u10d4 \u2014 \u10d4\u10e1 \u10ee\u10d3\u10d4\u10d1\u10d0 \u10db\u10d0\u10dc\u10d8\u10de\u10e3\u10da\u10d0\u10ea\u10d8\u10d0<\/p>\n<p>\u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0 \u10dc\u10d8\u10e8\u10dc\u10d0\u10d5\u10e1: \u10d4\u10e4\u10d4\u10e5\u10e2\u10e3\u10e0\u10dd\u10d1\u10d0, \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd\u10d4\u10d1\u10d0, \u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d4\u10d1\u10d0, \u10d3\u10d0 \u10d0\u10e0\u10d0 \u2014 \u10d4\u10db\u10dd\u10ea\u10d8\u10d0, \u10de\u10dd\u10da\u10d8\u10e2\u10d8\u10d9\u10d0, \u10dc\u10d0\u10ee\u10d4\u10d5\u10d0\u10e0\u10d8 \u10e1\u10d8\u10db\u10d0\u10e0\u10d7\u10da\u10d4&#8221;, &#8211; \u10ec\u10d4\u10e0\u10e1 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e8\u10d4\u10ea\u10d3\u10dd\u10db\u10d0 \u10d3\u10e6\u10d4\u10e1 \u10d0\u10e0\u10d8\u10e1 \u10d8\u10e1, \u10e0\u10dd\u10db \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10e1 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10e4\u10d0\u10e1\u10e1 \u10d3\u10d0 \u201e\u10d8\u10db\u10d4\u10d3\u10e1\u201c, \u10db\u10d0\u10d2\u10e0\u10d0\u10db \u10d0\u10e0 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10e1. \u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0\u10e8\u10d8 \u10e0\u10d8\u10e1\u10d9\u10d8\u10e1 \u10d3\u10d0\u10db\u10d0\u10da\u10d5\u10d0 \u2014 \u10d0\u10e0\u10d8\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10d4. \u10db\u10d7\u10d0\u10d5\u10d0\u10e0\u10d8 \u10e4\u10d0\u10e5\u10e2\u10d8 (\u10e0\u10d0\u10ea \u10d0\u10e3\u10ea\u10d8\u10da\u10d4\u10d1\u10da\u10d0\u10d3 \u10e3\u10dc\u10d3\u10d0 \u10d8\u10ea\u10dd\u10d3\u10d4\u10e1 \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10db), \u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd, \u10db\u10d0\u10e0\u10e2\u10d8\u10d5\u10d8 \u10d0\u10dc \u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0, &#8211; \u10ec\u10d4\u10e0\u10e1 \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10d4\u10e5\u10e1\u10de\u10d4\u10e0\u10e2\u10d8 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4 7 \u10d0\u10de\u10e0\u10d8\u10da\u10e1 \u10e1\u10dd\u10ea\u10d8\u10d0\u10da\u10e3\u10e0 \u10e5\u10e1\u10d4\u10da\u10e8\u10d8 \u10d2\u10d0\u10db\u10dd\u10e5\u10d5\u10d4\u10e7\u10dc\u10d4\u10d1\u10d8\u10da \u10de\u10dd\u10e1\u10e2\u10e8\u10d8. \u201e\u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10d9\u10e3\u10dc\u10d7\u10dd\u10d5\u10d0\u10dc\u10d8 [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":45297,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[283],"tags":[],"class_list":{"0":"post-55957","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-283"},"jetpack_featured_media_url":"https:\/\/mkhare.ge\/wp-content\/uploads\/2025\/10\/fxakadze-2021-12-13_13-31-27_077496.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/mkhare.ge\/index.php?rest_route=\/wp\/v2\/posts\/55957","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mkhare.ge\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mkhare.ge\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mkhare.ge\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/mkhare.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=55957"}],"version-history":[{"count":1,"href":"https:\/\/mkhare.ge\/index.php?rest_route=\/wp\/v2\/posts\/55957\/revisions"}],"predecessor-version":[{"id":55958,"href":"https:\/\/mkhare.ge\/index.php?rest_route=\/wp\/v2\/posts\/55957\/revisions\/55958"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mkhare.ge\/index.php?rest_route=\/wp\/v2\/media\/45297"}],"wp:attachment":[{"href":"https:\/\/mkhare.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=55957"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mkhare.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=55957"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mkhare.ge\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=55957"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}